Functional analysis of {Sec61β [Sec-61-beta], a component of the Sec61 protein translocation channel at the endoplasmic reticulum [Elektronische Ressource] / presented by Anshuman Kelkar

INAUGURAL-DISSERTATIONSubmitted to theCombined Faculties for the Natural Sciences and for MathematicsRupert-Karl-Universität Heidelbergfor the degree ofDoctor of Natural SciencesPresented byMaster of Science Anshuman KelkarBorn in: Aizwal, India2005Oral Examination:2Functional Analysis of Sec61β,A Component of theSec61 Protein Translocation Channel at theEndoplasmic ReticulumReferees:Professor Dr. Bernhard DobbersteinProfessor Dr. Dirk Görlich3AcknowledgementsTo make a list of people who I would like to thank would extend into several pages. So,although I will try to name a few, but I apologise right at the beginning to the people who Imay have forgotten to name. I am sure I will remember the help of every one.To being with I would of course like to thank Bernhard. I thank him not only for hissupport during my Phd, but also for his immense patience. I think I gave him some of thehardest time ever during our long discussion sessions. I also would like to thanks Dr. DirkGörlich for being my second referee.I would also like to thank the people in the lab past and present. It was great to haveMartin, Jeannie, Sumudhu, Joanne and Steffen around in the lab; I think Martin was kind ofmy mentor during my early days in the lab. Mathias and Peter were like elder brothers of thelab who one could turn to when things got bad or when a quick advice, without necessarilyinvolving Bernhard, was needed.