Evolutionary systems biology in yeast [Elektronische Ressource] / by Guang-Zhong Wang

Evolutionary Systems Biology in Yeast By Guang-Zhong Wang A thesis submitted to the Heinrich-Heine-Universität Düsseldorf for the degree of Doctor rerum naturalium (Dr. rer. nat.) Supervised by Professor Martin J. Lercher Institute of Computer Science Heinrich-Heine-University Düsseldorf June 2010 Aus dem Institut für Informatik der Heinrich-Heine-Universität Düsseldorf Gedruckt mit der Genehmigung der Mathematisch-Naturwissenschaftlichen Fakultät der Heinrich-Heine-Universität Düsseldorf Referent: Prof. Dr. Martin Lercher Korrferent: Prof. Dr. William Martin Tag der mündlichen Prüfung: August 25, 2010 Declaration This thesis is submitted for the degree of Doctor rerum naturalium at the Heinrich-Heine-University Düsseldorf. It has not been submitted to any other university for a degree. I agree that the University library may lend out or copy this thesis freely. Guang-Zhong Wang. June, 2010. Acknowledgements Many thanks to everybody in the Martin Lercher lab, past and present, for the creative scientific environment they provided: Gabriel Gelius-Dietrich, Wei-Hua Chen, Sabine Thuß, Thomas Laubach, Na Gao, Christian Eßer, Wolfgang Kaisers, Jan Wolfertz, Milan Majtanik and Janina Maß. A special thank you to the system administrators in the lab during my PhD, Jochen Kohl and Lutz Voigt, and to the secretary Anja Walge.