Engrailed genes are cell autonomously required for the survival of the mesencephalic dopaminergic neurons [Elektronische Ressource] / presented by Lavinia Alberi

DISSERTATIONsubmitted to theCombined Faculties for Natural Sciences and for Mathemathicsof the Ruperto-Carola University of Heidelberg, Germanyfor the degreeof Doctor of Natural SciencesPresented byLavinia Alberiborn in Trieste 24.07.19742004ENGRAILED GENES ARE CELL AUTONOMOUSLYREQUIRED FOR THE SURVIVAL OF THE MESENCEPHALICDOPAMINERGIC NEURONSReferees: Prof. Dr. BeyreutherProf. Dr. Witzemann"gnoqi s’ autón"ÂokrathsTABLE OF CONTENTSACKNOWLEDGMENTS........................................................................................IABBREVIATIONS ................................................................................................ IISUMMARY .............................................................................................................VINTRODUCTION................................................................................................... 11. General introduction.................................................................................................................................22. The dopaminergic system.........................................................................................................................32-1. Location of the midbrain DA neurons in the rodent brain ................................................................32-2. The dopaminergic afferent projections to the striatum .....................................................................42-3.