Efficacy, safety, tolerability and acceptability of two pediatric formulations of artesunate-mefloquine in African children with acute uncomplicated Plasmodium falciparum malaria [Elektronische Ressource] / vorgelegt von Sabine Miriam Bélard

Aus dem Institut für Tropenmedizin der Universität Tübingen Direktor: Professor Dr. J. Knobloch Sektion Humanparasitologie Leiter: Professor Dr. P. G. Kremsner Efficacy, Safety, Tolerability, and Acceptability of Two Paediatric Formulations of Artesunate-Mefloquine in African Children with Acute Uncomplicated Plasmodium falciparum Malaria Inaugural-Dissertation zur Erlangung des Doktorgrades der Medizin der Medizinischen Fakultät der Eberhard-Karls-Universität zu Tübingen vorgelegt von Sabine Miriam Bélard aus Filderstadt 2007 Dekan: Professor Dr. I. B. Autenrieth 1. Berichterstatter: Professor Dr. P. G. Kremsner 2. Berichterstatter: Professor Dr. C. H. Gleiter Table of Contents 1 1 Table of Contents _______________________________________________________________ 1 Table of Contents............................................................................................. 1 2 Introduction ....................................................................................................... 3 2.1 Treatment of Malaria .................................................................................. 3 2.2 Artesunate ................................................................................................... 5 2.3 Mefloquine................................................................................................... 7 2.4 The Antimalarial Combination Artesunate-Mefloquine ........