Effects of low-density lipoprotein receptor-related protein 4 and apolipoprotein E-isoforms on bone metabolism in vivo [Elektronische Ressource] / Marco Dieckmann

Effects of low-density lipoprotein receptor-related protein 4 and apolipoprotein E isoforms on bone metabolism in vivo Dissertation Zur Erlangung des Grades Doktor der Naturwissenschaften Am Fachbereich Biologie Der Johannes Gutenberg-Universität, Mainz Marco Dieckmann Geboren am 3. Februar 1980 in Bremen Mainz, November, 2010 1Dekan: 1. Berichterstatter: 2. Berichterstatter: Tag der mündlichen Prüfung: 3. Dezember 2010 2 Dedication This thesis is dedicated to my mother and my wife, who have supported me unconditionally 3 Copyright By Marco Dieckmann, 2010 All Rights Reserved 4ACKNOWLEDGMENTS I would first like to acknowledge my mentor Prof. Claus Pietrzik and Prof. Joachim Herz for giving me the opportunity to work, learn, and grow in their laboratories. Thank you for all your supervision, support, and encouragement during the past years. Thanks to all co-workers in the Pietrzik lab. Sebastian Jaeger, thanks for introducing me into this lab group. Your advice and our scientific discussions were very helpful to me. Thorsten Pflanzer, Timo Wagner, and Wladislaw Maier, it was always fun with you guys sharing the same lab - stay as you are. Simone Isbert, Anne Martin, and Bettina Andre-Dohmen, I enjoyed our time in lab and look forward to seeing you guys soon.