Effect of chromatin modeling by histone deacetylase inhibitors (HDIs) on hematopoietic stem cell (HSC) fate [Elektronische Ressource] / von D. Hilal Gül

Effect of Chromatin Modeling by Histone Deacetylase-inhibitors (HDIs) on Hematopoietic Stem Cell (HSC) FateDissertationZur Erlangung des Doktorgradesder Naturwissenschaftenvorgelegt beim Fachbereich Biochemie, Chemie und Pharmazieder Johann Wolfgang Goethe-Universitätin Frankfurt am MainvonD.Hilal Gülaus Ankara, TürkeiFrankfurt am Main 2005vom Fachbereich Biochemie, Chemie und Pharmazie der Johann WolfgangGoethe-Universität als Dissertation angenommenDekan: Prof. Dr. Harald SchwalbeGutachter: Prof. Dr. Rolf Marschalek Prof. Dr. Dieter HoelzerDatum der Disputation:2Acknowledgments:The present study was carried out in the Department of Hematology of the Johann Wolfgang-Goethe University Hospital in Frankfurt.It is a pleasure to thank many people who made this thesis possible.I wish to express my gratitude to Prof. Dr. Rolf Marschalek for taking the part ofresponsibility for this PhD study and being its referee as well as giving valuable advice andconstructive criticism.I wish to thank Prof. Dr. Dieter Hoelzer for allowing me to do a Ph.D. thesis in his departmentas well as for being external referee.I would like to thank to PD Dr. Martin Ruthardt, my group leader, for giving me theopportunity to work on a very exciting project and providing me the insight, advice, support,critics and knowledge in order to perform and complete this thesis project.I would also like to acknowledge PD Dr. Oliver Ottmann for his correctness, critics andkindness.