Distribution of I_1tnh channels and their function in the stomatogastric ganglion [Elektronische Ressource] / vorgelegt von Marie-Luise Göritz

Distribution of I Channels and their Function in the hStomatogastric Ganglion. I n a u g u r a l - D i s s e r t a t i o n zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultät der Universität zu Köln vorgelegt von Marie-Luise Göritz aus Marburg (Köln 2008) Berichterstatter: Prof. Dr. Peter Kloppenburg Prof. Dr. Joachim Schmidt Prof. Dr. Ron Harris-Warrick Tag der letzten mündlichen Prüfung: 8. Januar 2009 2 1 INTRODUCTION ........................................................................................................................8 1.1 RHYTHMICALLY ACTIVE NETWORKS................... 8 1.2 THE CRUSTACEAN STOMATOGASTRIC NERVOUS SYSTEM................................................10 1.3 THE HYPERPOLARIZATION-ACTIVATED INWARD CURRENT I......... 16 H1.4 HOMEOSTATIC RELATIONSHIP OF I AND I ....................................................................... 18 H A1.5 AIM OF THIS STUDY.............................................20 2 METHODS .................................................................................................. 21 2.1 STG DISSECTION AND PD CELL IDENTIFICATION..............................21 2.2 RNA MICROINJECTION INTO NEURONS .....