Development of mass spectrometric methods for the quantification of membrane lipids [Elektronische Ressource] : studies on mitochondria, T-cells, Golgi membranes and COPI vesicles / presented by Mathias Haag

Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences presented by Mathias Haag, Dipl.-Ing. (FH) Born: 25 May 1981 in Darmstadt Oral examination: 17 December 2010 Development of Mass Spectrometric Methods for the Quantification of Membrane Lipids – Studies on Mitochondria, T Cells, Golgi Membranes and COPI Vesicles Referees: Prof. Dr. Felix Wieland PD. Dr. Britta Brügger 2 List of publications Christof Osman, Mathias Haag, Felix T. Wieland, Britta Brügger and Thomas Langer “A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4“ EMBO J. 2010. Jun 16; 29(12); 1976-1987. Christof Osman, Mathias Haag, Christoph Potting, Jonathan Rodenfels, Phat Vinh Dip, Felix T. Wieland, Britta Brügger, Benedikt Westermann and Thomas Langer “The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria” J. Cell Biol. 2009. Feb 23; 184(4); 583-596. 3 Table of contents Abbreviations .................................................................................................................. 7 Abstract .........................................................................