Development and optimisation of calcium phosphate silica based ceramics for medical applications [Elektronische Ressource] / von Tania Traykova

Development and optimisation of calcium phosphate silica-based ceramics for medical applications Dissertation zur Erlangung eines akademischen Grades Doctor eines Wissenschaftszweiges (doctor rerum naturalium) vorgelegt der Matematisch-Naturwissenschaftlichen Fakultät der Universität Rostock von Tania Traykova Rostock, 2003 urn:nbn:de:gbv:28-diss2009-0077-5 Gutachter: Prof. Dr. Dr. V. Bienengräber – Universität Rostock Prof. Dr. Th. Gerber – Universität Rostock Prof. Dr. P. Behrens – Universität Hannover Verteidigt am 17 Juli 2003 FB Physik, Rostock To my parents Tinka and Valentin CONTENTS: Preface 1 Introduction……………………………………………………………………….……..1 1.1 Literature review……………………………………………………………………….1 1.2 Problems in replacing parts of the human body…………………………………….…3 1.3 Classification of ceramic biomaterials…………………………………………….…..5 1.4 A short overview of the medical usage of hydroxyapatite and tricalcium phosphate ceramics……………………………………………………………………9 1.5 Reasons for investigating biphasic calcium phosphate ceramics……………………10 2 Structure and composition of bone. Bone formation (osteogenesis) and bone remodelling. Bone grafts………………………………………………………………12 2.1 Bone structure………………………………………………………………….……12 2.2 Organic and mineral composition of bone……………………………………..……13 2.