Determination of neural crest cell fate at neural tube vs. target organ level [Elektronische Ressource] / presented by Marie Catherine Schier

Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences presented by PharmDr. Marie Catherine Schier Born in Vysoké Mýto, Czech Republic thOral-examination: 19 November 2009 Determination of Neural Crest Cell Fate at Neural Tube vs. Target Organ Level Referees: Prof. Dr. Klaus Unsicker Prof. Dr. Herbert Steinbeisser TABLE OF CONTENTS TABLE OF CONTENTS TABLE OF CONTENTS ................................................................................................ I ABSTRACT .................................................................................................................IV ZUSAMMENFASSUNG ........................................................................V 1 INTRODUCTION ................................................................................................... 1 1.1 NEURAL CREST ................................. 1 1.2 FATE OF NEURAL CREST CELL DERIVATIVES ........................................................ 2 1.2.1 Derivatives of NC ........................................................................................ 2 1.2.