Computational Modeling of Complex Reactions Kinetics in Biosensors ; Kompiuterinis daugiapakopių reakcijų kinetikos biojutikliuose modeliavimas

VILNIUSUNIVERSITY˙EvelinaGaidamauskaiteCOMPUTATIONALMODELINGOFCOMPLEXREACTIONSKINETICSINBIOSENSORSDoctoraldissertationPhysicalsciences,informatics(09P)Vilnius,2011Theworkwasperformedin2006-2011attheVilniusUniversity.Scientificsupervisor:prof. dr. Romas Baronas (Vilnius University, physical sciences, informatics -09P)VILNIAUSUNIVERSITETASEvelinaGaidamauskaite˙KOMPIUTERINISDAUGIAPAKOPIU˛REAKCIJU˛KINETIKOSBIOJUTIKLIUOSEMODELIAVIMASDaktarodisertacijaFiziniaimokslai,informatika (09P)Vilnius,2011Disertacijarengta2006-2011metaisVilniausuniversitete.Mokslinisvadovas:prof. dr. RomasBaronas(Vilniausuniversitetas, fiziniaimokslai, informatika -09P)AcknowledgementsFinancialsupportfromtheTheStateStudiesFoundationandresearchprojects:"Development of bioelectrocatalysis for synthesis and analysis (BIOSA)" fun-ded by the grant (No. PBT-04/2010) from the Research Council of Lithuaniaand "Developing computational techniques, algorithms and tools for efficientsimulationandoptimizationofbiosensorsofcomplexgeometry"fundedbytheEuropeanSocialFundunderMeasureVP1-3.1-ŠMM-07-K"SupporttoResearchofScientistsandOtherResearchers(GlobalGrant)"isgratefullyacknowledged.Letmeexpressmygratitudetothepeoplewhohavehelpedmeinmanyways.My first words of gratitude are due to my supervisor, prof. Romas Baronas,for introducing me to the problem of numerical modeling of biosensors, foracademic guidance and for the invaluable patience over these last years. It isanhonorformetothankprof.