Computational modeling and remodeling of human eye tissues as biomechanical structures at multiple scales [Elektronische Ressource] / von Rafael Grytz

Computational Modeling andRemodeling of Human Eye Tissuesas Biomechanical Structuresat Multiple ScalesVon der Fakult¨at fur¨ Bau- und Umweltingenieurwissenschaftender Ruhr-Universit¨at Bochum zur Erlangung desGrades Doktor-Ingenieur (Dr.-Ing.) genemigteDissertationvonDipl.-Ing. Rafael GrytzBochum, im August 2008Tag der Einreichung: 12. August 2008Tag der mu¨ndlichen Pru¨fung: 5. Dezember 2008Hauptreferent: Prof. Dr. techn. Gun¨ ther MeschkeLehrstuhl fur¨ Statik und DynamikFakult¨at fur¨ Bau- und UmweltingenieurwissenschaftenRuhr-Universit¨at BochumKorreferenten: Prof. Dr.-Ing. Stefanie ReeseInstitut fu¨r Festk¨orpermechanikFakult¨at fur¨ MaschinenbauTechnische Universit¨at Carolo-Wilhelmina zu BraunschweigProf. Dr. med. Jost B. JonasInstitut fu¨r OphthalmologieFakult¨at fur¨ klinische Medizin MannheimRuprecht-Karls-Universit¨at HeidelbergFu¨r meine Eltern.SummaryThis thesis is concerned with the biomechanical modeling of human eye tissueswithin a multi-scale framework considering the micro-, meso-, and macro-structure in the context of constitutive formulation, computational modelingand remodeling. Consideration of the heterogeneous tissue substructures openspromising perspectives for more realistic biomechanical modeling and compu-tational simulations of the human eye in physiological and pathophysiologicalconditions.