Comparative analysis of fine and nanoparticles for cellular uptake, oxidative stress and genomic damage in human lung cells [Elektronische Ressource] / presented by Kunal Bhattacharya

Comparative analysis of fine and nanoparticles for cellular uptake, oxidative stress and genomic damage in human lung cells Inaugural Dissertation for the Degree of Doctor of Natural Science Dr. rer. nat. A Thesis Presented to The Faculty of Biology and Geography University of Duisburg-Essen Germany Presented by Kunal Bhattacharya from Lucknow, India March, 2008 Die der folgenden Arbeit zugrunde liegenden Experimente wurden in der Arbeitgruppe ‘In-vitro- und Molekulare Toxikologie’ am Institut für Hygiene und Arbeitsmedizin der Universität Duisburg–Essen, durchgeführt. 1. Gutachter: 2. Gutachter: 3. Gutachter: Vorsitzender des Prüfungsausschusses: Tag der mündlichen Prüfung: Dedicated to my Parents The following publications were written during my doctoral tenure at the Institute of Hygiene and Occupational Medicine, University of Duisburg–Essen, and are partially attached to this thesis: o Dopp, E., Yadav, S., Ansari, F.A., Bhattacharya, K., von Recklinghausen, U., Rauen, U., Rödelsperger, K., Geh, S., Rahman, Q. (2005). ROS-mediated genotoxicity of asbestos-cement in mammalian lung cells in vitro. Part. Fibre Toxicol. 2, 9. o Bhattacharya, K., Dopp, E., Kakkar, P., Jaffery, F.N., Rahman, I., Jaurand, M.C., Rahman, Q. (2005). Biomarkers in risk assessment of asbestos exposure. Mutat. Res. 579(1-2), 6-21. o Bhattacharya, K., Alink, G.M.