Chromatin condensation during Drosophila spermiogenesis and decondensation after fertilization [Elektronische Ressource] / Sunil Jayaramaiah Raja

Chromatin condensation during Drosophila spermiogenesis and decondensation after fertilization Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften (Dr. rer. nat.) dem Fachbereich Biologie Philipps-Universität Marburg -Entwicklungsbiologie- Sunil Jayaramaiah Raja Marburg/Lahn 2005 This analysis was carried out from March 2002 to March 2005 at the Fachbereich Biologie (Entwicklungsbiologie) of Philipps-Universität Marburg under the supervision of Prof. Dr. Renate Renkawitz-Pohl. Vom Fachbereich Biologie Der Philipps-Universität Marburg als Dissertation am 20.05.2005 angenommen. Erstgutachter: Prof. Dr. Renate Renkawitz-Pohl Zweitgutachter: Prof. Dr. Guntram Suske Tag der mündlichen Prüfung: 20.05.2005 I Table of contents 1. Sumary 1 2. Introduction 3 2.1 Why study „Spermatogenesis“ ? 3 2.2 Structure and cytology of Drosophila melanogaster spermatogenesis 3 2.3 Germinal Proliferation center 2.4 Primary spermatocyte growth phase 4 2.4.1 Translational repression 5 2.5 Spermatid Differentiation 7 2.5.1 Onion Stage spermatid 7 2.5.2 Spermatid elongation and maturation 8 2.5.3 Morphological changes in the mitochondrial derivative during the elongation stage 8 2.6 Chromatin condensation and nuclear shaping 9 2.6.