Characterization of the yeast proteins Neo1p and Sjl2p, two highly conserved regulators of phospholipid composition within endosomal membranes [Elektronische Ressource] / vorgelegt von Sidonie Wicky John

Characterization of the yeast proteins Neo1p and Sjl2p,two highly conserved regulatorsof phospholipid composition within endosomal membranesVon der Fakultät Geo- und Biowissenschaften der Universität Stuttgartzur Erlangung der Würde eines Doktors derNaturwissenschaften (Dr. rer. Nat.) genehmigte Abhandlungvorgelegt vonSidonie Wicky Johnaus Schelten (Schweiz)Hauptberichter: Priv.-Doz. Dr. Birgit Singer-KrügerMitberichter: Prof. Dr. Dieter H. WolfTag der mündlichen Prüfung: 15.12.2004Institut für Biochemie der Universität Stuttgart200412Table of contentsAbbreviations............................................................................................................................5Zusammenfassung....................................................................................................................6Abstract...................................................................................................................................141 Introduction .........................................................................................................................161.1 Endocytosis in the budding yeast Saccharomyces cerevisiae................................................. 161.1.1 Yeast as a model for studying endocytosis......................................................................... 161.1.2 The endocytic compartments.............................................................................................. 161.