Characterization of neuronal activity in the auditory brainstem of rats [Elektronische Ressource] : an optical imaging approach / vorgelegt von Geetha Srinivasan

Characterization of neuronal activity in the auditory brainstem of rats: An optical imaging approach Dissertation zur Erlangung des Doktorgrades der Naturwissenschaften Fachbereich Biologie Technische Universität Kaiserslautern vorgelegt von Geetha Srinivasan Juni 2004 Vorsitzender: Prof. Dr. Joachim W. Deitmer (Technische Universität Kaiserslautern) Betreuer: Prof. Dr. Eckhard Friauf (Technische Universität Kaiserslautern) Koreferent: Prof. Dr. Rüdiger Köhling (Rheinische Friedrich-Wilhelms-Universität Bonn) Tag der Disputation: Juli 2004 I, Geetha Srinivasan, do hereby declare that this submission is my own work and that, to the best of my knowledge and belief, it contains no material previously published by another person, nor material which to a substantial extent has been accepted for the award of any other degree or diploma of a university or other institute of higher learning. thKaiserslautern, 14 June 2004. Table of contents 1 General introduction 1 1.1 Auditory pathway - an overview 1 1.2 Superior olivary complex - an integral part of the central auditory system 2 1.3 Multisite optical recording of the SOC complex 7 1.4 Aim of this thesis 9 2 Establishment of optical imaging with voltage-sensitive dye in auditory brainstem slices 10 2.1 Introduction 10 2.