Characterization of LINA, a new RING-Finger protein with axon growth promoting activity [Elektronische Ressource] / vorgelegt von Jieun Lee

Characterization of LINA a new RING-Finger protein with axon growth promoting activity Dissertation zur Erlangung des Doktorgrades Dr. rer. nat. der Fakultät für Naturwissenschaften der Universität Ulm vorgelegt von Jieun Lee aus Samchok, Südkorea 2009 2 Amtierender Dekan: Prof. Dr. Peter Bäuerle Erster Gutachter: Prof. Dr. Harald Wolf Zweiter Gutachter: Dr. Wolfgang Stein Tag der mündlichen Prüfung: 15.06.2009 Contents 3 Contents Contents....................................................................................................3 Figures ......................................................................................................6 Abstract.....................................................................................................7 Zusammenfassung...................................................................................8 Abbreviations............................................................................................9 1 Introduction ..................................................................................13 1.1 The visual system...........................................................................13 1.2 Difference of glial environment between CNS and PNS.................15 1.2.1 Myelin inhibitory proteins ........................................................................ 16 1.2.2 The glial scar ....