Characterization of dendritic cells generated from acute myeloid leukemia blasts as a potential cancer vaccine [Elektronische Ressource] / Li Li

id1038303 pdfMachine by Broadgun Software - a great PDF writer! - a great PDF creator! - http://www.pdfmachine.com http://www.broadgun.com Abteilung Innere Medizin III Universität Ulm ˜rztlicher Direktor: Prof. Dr. med. Hartmut Döhner Characterization of dendritic cells generated from acute myeloid leukemia blasts as a potential cancer vaccine Dissertation for the attainment of the Doctor Degree of Medicine (Dr. med.) at the Faculty of Medicine, University of Ulm Presented by Li Li born in Xinyang, Henan, P. R. China 2005 Amtierender Dekan: Prof. Dr. Klaus-Michael Debatin 1. Berichterstatter: PD Dr. med. Michael Schmitt 2. Berichterstatter: PD Dr. med. Willy Flegel Tag der Promotion: 08-July-2005 Table of Content Content 1 Introduction …………………………………………………… ... …… .. .. 1 1.1 Acute myeloid leukemia .………………………………… ...…………… .. . 1 1.1.1 Cytogenetic analysis …………………… ...………… . … ...…………… .. .. 1 1.1.2 Classification of AML ………………………… ...…………………… . .. .. . 2 1.1.3 Novel therapeutical agents for AML ………………………………… ... .. 3 1.2 Dendritic cells (DCs) ………………………… .…………………… ...… . 5 1.3 Tumor associated antigens (TAAs) …… .………………… .. .. ..… .. .. 7 1.3.1 Definition of TAAs ………………………………………………… ... .. . 7 1.3.2 Classification of TAAs ……………………… ...…………………… . …… . 8 1.3.