Cellular, biochemical and phylogenomic analyses of the mouse Jumonji domain containing 6 protein provide new evidence for functions as a 2-oxoglutarate dependent dioxygenase [Elektronische Ressource] / von Phillip Holgar Heinrich Hahn

Cellular, biochemical and phylogenomic analyses of the mouse Jumonji domain containing 6 protein provide new evidence for functions as a 2-oxoglutarate dependent dioxygenase Von der Fakultät für Lebenswissenschaften der Technischen Universität Carolo-Wilhelmina zu Braunschweig zur Erlangung des Grades eines Doktors der Naturwissenschaften (Dr. rer. nat.) genehmigte D i s s e r t a t i o n von Phillip Holgar Heinrich Hahn aus Georgsmarienhütte 1. Referentin oder Referent: Prof. Dr. Rudi Balling 2. Referentin oder Referent: Prof. Dr. Jürgen Wehland eingereicht am: 07.11.2007 mündliche Prüfung (Disputation) am: 20.12.2007 Druckjahr: 2008 Table of contents 1 Table of contents TABLE OF CONTENTS ............................................................................................. 1 SUMMARY ................................................................................................................. 4 1.  INTRODUCTION ................................................................................................ 5 1.1  The phosphatidylserine receptor ............................................................................................... 5 1.1.1  The phosphatidylserine receptor and its proposed function in apoptotic cell clearance ....... 5 1.1.