Approaches to isolating a cDNA encoding thebaine synthase of morphine biosynthesis from opium poppy Papaver somniferum L. [Elektronische Ressource] / von Khaled Sabarna

Martin-Luther-Universität Halle-Wittenberg Fachbereich Biochemie/Biotechnologie Approaches to isolating a cDNA encoding thebaine synthase of morphine biosynthesis from opium poppy Papaver somniferum L. Dissertation zur Erlangung des akademischen Grades doctor rerum naturalium (Dr. rer. nat.) vorgelegt der Mathematisch-Naturwissenschaftlich-Technischen Fakultät (mathematisch-naturwissenschaftlicher Bereich) der Martin-Luther-Universität Halle-Wittenberg von Herrn Khaled Sabarna geb. am 10.10.1969 in Palestine Gutachter 1. Prof. Dr. Toni M. Kutchan 2. Prof. Dr. Martin J. Müller Halle (Saale), den 12.06.2006 Verteidigungsdatum: 16.11.2006urn:nbn:de:gbv:3-000010922[ http://nbn-resolving.de/urn/resolver.pl?urn=nbn%3Ade%3Agbv%3A3-000010922 ] With all love I dedicate this work to my mother, may God bless her Khaled Content Content I. Introduction 1 I.1 Plant secondary metabolism 1 I.2 Modern methods of gene discovery 2 I.3 Single- cell genomic 3 I.4 Enzymes of plant secondary metabolism 4 I.4.1 Substrates and products 4 I.4.2 Evolution and function 5 I.5 Multiple levels of regulation of plant secondary pathways 6 I.5.1 Metabolon formation and metabolic channeling in secondary metabolism 6 I.5.