Analysis of the role of the E-(epithelial) cadherin in murine lung tumorigenesis [Elektronische Ressource] / Fatih Ceteci

ANALYSIS OF THE ROLE OF THE E-(Epithelial) CADHERIN IN MURINE LUNG TUMORIGENESIS Dissertation For completion of the Doctorate degree in Natural Sciences at the Bayerische Julius-Maximilians-Universität Würzburg Oleg Tyrsin Fatih Ceteci from Solingen, Germany Würzburg 2008 The hereby submitted thesis was completed from Jun 2002 until Jun 2008 at the Institute for Medical Radiation and Cell Research (MSZ), Bayerische Julius-Maximilians University, Würzburg under the supervision of Prof. Dr. Ulf R. Rapp (Faculty of Medicine) and PD Dr. R. Götz (Faculty of Medicine). Submitted on: Members of the thesis committee: Chairman: Prof. Dr. Ulf R. Rapp Examiner: PD Dr. R. Götz Examiner: Prof. Dr. R. Benavente Date of oral exam: Certificate issued on: ACKNOWLEDGMENTS It is a pleasure to thank the many people who made this thesis possible. I would like to express my deep and sincere gratitude to Prof. Dr. Ulf R. Rapp who allowed me to undertake my Ph.D. research in the MSZ Institute. It is difficult to overstate my gratitude to him not only for inviting me to the MSZ but also for his strong scientific guidance as well as for providing enthusiasm, inspiration, and strong motivation during my studies. His wide knowledge and his logical way of thinking have been of great value for me.