Analysis of maturation of measles virus hemaglutinin in yeast S. cerevisiae and P. pastoris secretory pathway and humanization of yeast cells ; Tymų viruso hemagliutinino baltymo brendimo procesų mielių S. cerevisiae ir P. pastoris ląstelių sekreciniame kelyje tyrimas ir mielių humanizavimas

VILNIUS UNIVERSITY Evaldas iplys ANALYSIS OF MATURATION OF MEASLES VIRUS HEMAGLUTININ IN YEAST S. CEREVISIAE AND P. PASTORIS SECRETORY PATHWAY AND HUMANIZATION OF YEAST CELLS Summary of doctoral dissertation Physical sciences, biochemistry (04 P) Vilnius, 2011 This study was carried out in the Laboratory of Eukaryote Genetic Engineering of the Institute of Biotechnology, Vilnius University, during 2007-2011. Scientific supervisor: Dr. Rimantas Slibinskas (Institute of Biotechnology, Vilnius University, physical sciences, biochemistry – 04 P). Scientific consultant: Prof. Habil. Dr. Habil. Kstutis Sasnauskas (Institute of Biotechnology, Vilnius University, biomedical sciences, biology – 01 B). Evaluation board of dissertation of Biochemistry trend: Chairman: Dr. Gintautas Žvirblis (Institute of Biotechnology, Vilnius University, physical sciences, biochemistry – 04 P). Members: Dr. Aurelija Žvirblien (Institute of Biotechnology, Vilnius University, biomedical sciences, biology – 01 B); Dr. Giedrius Vilkaitis (Institute of Biotechnology, Vilnius University, physical sciences, biochemistry – 04 P); Dr. Arnas Lagunaviius (Thermo Fisher Scientific, physical sciences, biochemistry – 04 P); Dr. Artras Jakubauskas (VUH Santariški clinics, Center of Hematology, Onkology and Transfuzion, physical sciences, biochemistry – 04 P). Opponents: Prof. Habil. Dr.