Alternative splicing of calcium channel Ca_1tnv1.1 [Elektronische Ressource] / submitted by Natalia Anna Molenda

University of Ulm Department of Applied Physiology Prof. Dr. med. Dr. hc. Frank Lehmann-Horn Alternative splicing of calcium channel Ca 1.1 V Dissertation Applying for the degree of Doctor of human biology (Dr. biol. hum.) Faculty of Medicine, University of Ulm Submitted by Natalia Anna Molenda from Koszalin, Poland Ulm, 2007 Amtierender Dekan: Prof. Dr. Klaus-Michael Debatin 1. Berichterstatter: PD Dr. Karin Jurkat-Rott 2. Berichterstatter: Prof. Dr. Jürgen Steinacker Tag der Promotion: 20.07.2007 Contents LIST OF ABBREVIATIONS I. INTRODUCTION.............................................................................................................. 1 I.1. Calcium channel.......................................................................................................... 1 I.1.1. Calcium channel family ....................................................................................... 1 I.1.2. Calcium channel structure and function............................................................... 2 I.1.3. Ca 1.1 calcium function ...................................................................................... 5 VI.2. Pre-mRNA splicing..................................................................................................... 7 I.2.1. Signification of splicing 7 I.2.2. Basic splicing reaction .......................................................................