Affective reactivity in clinical depression [Elektronische Ressource] : development of an experimental paradigm / vorgelegt von Katrin R. Scharpf

Affective Reactivity in Clinical Depression:Development of an Experimental ParadigmDer Philosophischen Fakultätder Ernst Moritz ArndtUniversität GreifswaldeingereichteDISSERTATIONzur Erlangung des akademischen GradesDr. phil.vorgelegtvon Katrin R. Scharpfgeboren am 10. Juli 1979 in FreiburgDekan:Professor Dr. Matthias SchneiderGutachter:Professor Dr. A. HammProfessor Dr. M. LotzeTag der Dispuation: 29.10.2008AcknowledgmentsI want to thankKatharina and Thomas for the good companionshipHeino for the technical supportSusan for the agency of the patientsJulia for the introduction and support with the fMRI projectthe rest of the gang for a working atmosphere in friendship and cooperativenessand last but not least all participants without them, this thesis would not exist.Contents1 Introduction 32 Background 72.1 Depressive Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72.1.1 Diagnosis and Classification . . . . . . . . . . . . . . . . . . . . . 72.1.2 Epidemiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92.2 Affective Disturbances in Clinical Depression . . . . . . . . . . . . . . . . 142.2.1 Negative Potentiation . . . . . . . . . . . . . . . . . . . . . . . . . 152.2.2 Positive Attenuation . . . . . . . . . . . . . . . . . . . . . . . . . 162.2.3 Emotion Context Insensitivity . . . . . . . . . . . . . . . . . . . . 172.3 Experimental Methods of Affect Induction . . . . . . . . . . . . . . . . . . 202.