A theoretical model on the role of lateral gene transfer in the evolution of endosymbiotic genomes [Elektronische Ressource] / Víctor Hugo Anaya Munoz. Gutachter: Peter Hammerstein ; Hans-Jörg Rheinberger ; Daniel Piñero Dalmau

A Theoretical Model on the Role of Lateral GeneTransfer in the Evolution of Endosymbiotic GenomesDISSERTATIONzur Erlangung des akademischen GradesDoctor Rerum Naturaliumim Fach Biologieeingereicht an derMathematisch-Naturwissenschaftlichen Fakultät IHumboldt-Universität zu BerlinvonDipl. Biol. Víctor Hugo Anaya Muñoz , M.Sc.geboren am 03.06.1977 in Mexiko Stadt, MexikoPräsident der Humboldt-Universität zu Berlin:Prof. Dr. Jan-Hendrik OlbertzDekan der Mathematisch-Naturwissenschaftlichen Fakultät I:Prof. Dr. Andreas HerrmannGutachter:1. Prof. Dr. Peter Hammerstein2. Prof. Dr. Hans-Jörg Rheinberger3. Prof. Dr. Daniel Piñero Dalmaueingereicht am: 28. April 2010Tag der mündlichen Prüfung: 25.Oktober 2010AbstractLateral gene transfer has played a key role in the evolution of living beings. Thisprocess was first acknowledged in (1978) by Schwartz and Dayhoff but considereda relatively infrequent eccentricity and ignored. Later on, as DNA and proteinsequences accumulated and more refined phylogenies were reconstructed, the con-tribution of lateral (or horizontal) gene transfer to the evolutionary history of livingorganisms gained relevance. Besides, gene transfer is known to occur not only be-tween independent organisms but also, and more frequently between endosymbiontsincluding eukaryotic organelles. I developed a theoretical model to study the lateralgenetransferprocessbetweencellorganelles(butextendibletootherendosymbionts)and the cell nucleus.