A new model of pharmacoresistant seizure like events and age specific effects of antiepileptic drugs [Elektronische Ressource] / von Abdul Wahab

Aus dem Institut für Neurophysiologie der Medizinischen Fakultät Charité – Universitätsmedizin Berlin DISSERTATION A new model of pharmacoresistant seizure like events and age specific effects of antiepileptic drugs zur Erlangung des akademischen Grades Doctor of Philosophy in Medical Neurosciences (PhD in Medical Neurosciences) vorgelegt der Medizinischen Fakultät Charité – Universitätsmedizin Berlin von Abdul Wahab Aus Hyderabad, Pakistan Gutachter: 1. Prof. Dr. U. Heinemann 2. Prof. Dr. H. Potschka 3. Prof. Dr. A. Friedman Datum der promotion: 19.11.2010 II Table of Contents List of Abbreviations.......................................................................................................................... IV List of Figures................................................................................................ IV Summary........................................................................................................ V 1. Introduction and aims........................................................................................................... 1 2. Methods........................................................ 2 2.1. Preparation of organotypic hippocampal slice cultures (OHSCs)………………….......... 2 2.2.