Developmental biology and tissue engineering

Developmental Biology and Tissue Engineering Francoise Marga, Adrian Neagu, Ioan Kosztin, and Gabor Forgacs* Morphogenesis implies the controlled spatial organization of cells that gives rise to tissues and organs in early embryonic development. While morphogenesis is under strict genetic control, the formation of special- ized biological structures of specific shape hinges on physical processes. Tissue engineering (TE) aims at reproducing morphogenesis in the labo- ratory, i.e.

• primitive heart tube
• bio-paper
• tube- like
• like pellet that forms along the wall of the centrifuge tube
• self-assembly
• pellet
• fusion
• tissue
• cell
• cells
• 2 cells