Phase 2 Results Show INCIVO® (telaprevir), in Combination With Peginterferon Alfa and Ribavirin, is Effective in Treating Patients Co-infected With Genotype-1 Chronic Hepatitis C Virus and HIV

Phase 2 Results Show INCIVO® (telaprevir), in Combination With Peginterferon Alfa and Ribavirin, is Effective in Treating Patients Co-infected With Genotype-1 Chronic Hepatitis C Virus and HIV PR Newswire BOSTON, Massachusetts, November 10, 2012 BOSTON, Massachusetts, November 10, 2012 /PRNewswire/ -- - Study presented at American Association for the Study of Liver Diseases 2012 shows high sustained virological response (SVR) in HCV/HIV co-infected patients receiving INCIVO® (telaprevir)-based regimen - Janssen Infectious Diseases-Diagnostics BVBA (Janssen) today presented results from a new phase 2 study which shows that an INCIVO® (telaprevir)-based regimen was effective in achieving a sustained virological response at 24 weeks (SVR24) in patients co-infected with both genotype-1 chronic hepatitis C virus (HCV) and HIV (HCV/HIV) compared to patients receiving a placebo with the standard HCV treatment, peginterferon alfa and ribavirin (74 vs. 45 [1]percent). [2]An estimated 130 to 210 million people are infected with HCV worldwide , with HCV/HIV co-infections averaging [3]about 40 percent of HCV patients in Europe. People co-infected with HCV/HIV have more rapid fibrosis progression [3]and liver disease than patients with HCV alone. Chronic HCV infections can lead to end-stage liver disease, which is [3]a major cause of death in HCV/HIV co-infected patients.