First Clinical Data for BACE Inhibitor E2609 Showcased at International Alzheimer's Conference

First Clinical Data for BACE Inhibitor E2609 Showcased at International Alzheimer's Conference PR Newswire HATFIELD, England, July 24, 2012 HATFIELD, England, July 24, 2012 /PRNewswire/ -- Eisai's new investigational molecule discovered and developed collaboratively in the UK and Japan Eisai in Europe today releases the first clinical data for E2609, a BACE (beta-site amyloid precursor protein-cleaving enzyme) inhibitor, presented during oral sessions at the Alzheimer's Association International Conference (AAIC) 2012 in Vancouver, Canada. This novel compound was discovered through a collaborative partnership between centres in Britain, Japan and the United States (US). Eisai's European Knowledge Centre is in Hatfield, UK. Eisai has one of the largest private dementia research groups in Britain. Through collaborative efforts with partners in the UK and colleagues in Japan, this group has been a part of key neurological discoveries including the potential new treatment for epilepsy, Fycompa® (perampanel), and now E2609. Amyloid beta (Aβ) deposition in the brain is thought to be one of the causes of Alzheimer's disease. It is expected that developing a new treatment for Alzheimer's disease which reduces amyloid beta will not only improve symptoms, but also help slow down the progression of the disease. E2609 may reduce the overall amount of amyloid beta by inhibiting BACE.