A General Model for the Origin of Allometric Scaling Laws in Biology

p888, which contains a Bam HI to Not I fragment AGeneralModelfortheOriginofAllometricencoding a full-length profilin cDNA (16); p989,which encodes a mutant form of profilin, Pfy1p-3, ScalingLawsinBiologylackingthelastthreeaminoacids(18);p890,whichcontainstheBglIItoStuIfragmentfromp182(26),encoding Bni1p(1227–1397); p813, which con- Geoffrey B. West, James H. Brown,* Brian J. EnquisttainstheBglIItoNotIfragmentfromp182,encod-ing Bni1p(1414–1953); and p951, which contains Allometric scaling relations, including the 3/4 power law for metabolic rates, are char-the Hpa I to Not I fragment from p182, encoding acteristicofallorganismsandareherederivedfromageneralmodelthatdescribeshowBni1p(1647–1953).ThepJG4-5–derivedplasmidsessential materials are transported through space-filling fractal networks of branchingwere p561, which contains the Bam HI to Not Ifragmentfromp532(26),encodingBni1p(1–1953); tubes.Themodelassumesthattheenergydissipatedisminimizedandthattheterminalp717,whichcontainstheBamHItoEco47IIIfrag- tubesdonotvarywithbodysize.Itprovidesacompleteanalysisofscalingrelationsforment from p532, encoding Bni1p(1–1214); p558,mammalian circulatory systems that are in agreement with data. More generally, thewhichcontainstheEco47IIItoNotIfragmentfromp182, encoding Bni1p(1215–1953); p913, which model predicts structural and functional properties of vertebrate cardiovascular andcontains the Bgl II to Stu I fragment from p182, respiratorysystems,plantvascularsystems ...