biomed

Savoirs

MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to, and affecting Tax-2 intracellular localization

Orlandi Chiara, Forlani Greta, Tosi Giovanna, Accolla

Savoirs

The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T-Cell Lymphotropic Virus Type 1

Genoveffa Franchini, Tosi Giovanna, Forlani Greta, Andresen Vibeke, Turci Marco, Bertazzoni Umberto, Accolla

Savoirs

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

Kuo Chien-Wen, Tulloch Lindsay, Brighty

Savoirs

Development of a real time PCR assay using SYBR Green chemistry for bovine leukemia virus detection

Rama Gonzalo, Moratorio Gonzalo, Greif Gonzalo, Obal Gonzalo, Bianchi Sergio, Tomé Lorena, Carrion Federico, Meikle Ana, Pritsch, Pritsch Otto

Savoirs

Cloned HTLV-1+CD4+, but not CD8+, T-cells display an oncogenic miRNome

Vernin Céline, Pinatel Christiane, Nazaret Nicolas, Wattel Eric, Legras-Lachuer Catherine, Mortreux, Mortreux Franck

Savoirs

HTLV-1 modulates alternative splicing in CD4+ T cells in vivo

Thenoz Morgan, Vernin Céline, Pinatel Christiane, Nazaret Nicolas, Lachuer Joel, Auboeuf Didier, Wattel Eric, Mortreux, Mortreux Franck

Savoirs

Stromal cells help ATL cells to escape from apoptosis induced by histone deacetylase inhibitors

Miyatake Yukiko, Tomaru Utano, Sheehy Noreen, Yoshiki Takashi, Kasahara Masanori, Oliveira, Hall

Savoirs

Overexpression of SIRT1 and induction of apoptosis by its inhibition in adult T-cell leukemia cells

Kozako Tomohiro, Aikawa Akiyoshi, Shoji Teruhisa, Yoshimitsu Makoto, Shimeno Hiroshi, Soeda Shinji, Uozumi Kimiharu, Arima, Arima Naomichi

Savoirs

Pattern mRNA expression similarities between ATL patients and patients coinfected with HTLV-I-Strongyolides stercoralis

Talledo Michael, López Giovanni, Verdonck Kristien, González Elsa, Tipismana Martin, Gotuzzo Eduardo, Clark, Daniel Clark

Savoirs

Transformation of human embryonic stem cells by HTLV-1 Tax

Zane Linda, Yasunaga Junichiro, Kinjo Takao, Jeang, Jeang Kuan-Teh, De

Savoirs

Comparative structural analysis of retroviral fusion proteins identifies regions that modulate membrane fusion: a potential retroviral achilles heal?

Lamb Daniel, Schüttelkopf, Brighty, Van

Savoirs

A specificity map for HTLV-1 Tax/PDZ interactions

Blibek Karim, Twizere, Twizere Jean-Claude

Savoirs

Regulation of AP-1 activity by the HTLV-2 APH-2 protein

Marban Céline, Sheehy Noreen, Sheehy, Hall

Savoirs

Physical and functional interaction between the HTLV-1 Tax oncoprotein and the cellular LIM domain protein FHL3

Mccabe Áine, Sheehy Noreen, Hall, Sheehy

Savoirs

Kinome profiling of BLV-induced ovine leukemia: an approach for identifying altered signaling pathways associated with oncogenesis

Van, Arsenault Ryan, Rosewick Nicolas, Cleuter Yvette, Martiat Philippe, Burny Arsène, Napper Scott, Griebel, Griebel Philip

Savoirs

Localization and sub-cellular shuttling of HTLV-1 Tax with the RNAi machinery component Drosha

Van, Guendel Irene, Tyagi Mudit, Narayanan Aarthi, Klase Zachary, Kehn-Hall Kylene, Semmes John, Kashanchi, Kashanchi Fatah

Savoirs

The human T-cell leukemia virus type I (HTLV-I) oncoprotein Tax promotes persistent NF-κB activation by blocking the phosphorylation of the adaptor molecule TAX1BP

Shembade Noula, Harhaj

Savoirs

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis

Fu Jing, Qu Zhaoxia, Yan Pengrong, Li Shirong, Song Xinxin, Ishikawa Chie, Aqeilan, Mori Naoki, Rabson, Xiao, Xiao Gutian

Savoirs

MicroRNA expression in HTLV-1 infection and pathogenesis

D'Agostino, Ruggero Katia, Biasiolo Marta, Bortoluzzi Stefania, Pise-Masison, Corradin Alberto, Basso Katia, Guffanti Alessandro, De, Corti Giorgio, Zanovello Paola, Bronte Vincenzo, Ciminale Vincenzo

Savoirs

HTLV-1 HBZ activates mTOR signaling pathway via inhibition of GADD34

Mukai Risa, Ohshima, Ohshima Takayuki

Savoirs

Control of ROS production and T-cell turnover by HTLV-p13

Silic-Benussi Micol, Cavallari Ilaria, Chieco-Bianchi Luigi, Di, D’Agostino, Bernardi Paolo, Ciminale, Ciminale Vincenzo

Savoirs

HTLV-1 Tax directly modulates expression of the CDK6 and RNASET2 genes

Polakowski Nicholas, Han Hongjin, Lemasson Isabelle, Le Masson

Savoirs

HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation

Higuchi Masaya, Fujii, Fujii Masahiro

Savoirs

HTLV-1 evades Type 1 interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1)

Olière Stéphanie, Hernandez Eduardo, Lézin Agnès, Douville Renée, Césaire Raymond, Hiscott, Hiscott John

Savoirs

HBZ inhibits the HAT activity of the cellular coactivators p300 and CBP

Wright Diana, Wurm Torsten, Polakowski Nicholas, Mesnard Jean-Michel, Lemasson Isabelle, Le Masson

Savoirs

High-throughput sequencing reveals novel microRNAs in the Bovine Leukemia Virus (BLV)-induced ovine model of leukemia

Rosewick Nicolas, Dehouck Céline, Cleuter Yvette, Caiment Florian, Martiat Philippe, Burny Arsène, Van, Georges Michel

Savoirs

TP53 and p16INK4A mutations in adult-T cell leukemia/lymphoma (ATL) in Bahia (Brazil)

Magalhães Marcelo, Salvino, Farre, Bittencourt Achiléa, Farré Lourdes

Savoirs

Microsatellite instability in the smoldering form of adult T-cell leukemia/lymphoma (ATL) in Brazil

Bittencourt, Magalhães Marcelo, Bittencourt Achiléa, Farré Lourdes

Savoirs

Host genetic factors associated to proviral load in Peruvian HTLV-1 infected

Talledo Michael, López1 Giovanni, Huyghe, Verdonck Kristien, González Elsa, Tipismana Martin, Vanham Guido, Gotuzzo Eduardo, Van, Daniel Clark

Savoirs

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Kfoury Youmna, Setterblad Niclas, El-Sabban Marwan, Zamborlini Alessia, Dassouki Zeina, El, Hermine Olivier, Pique Claudine, Bazarbachi Ali, De, Saib Ali